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• Fatigue, Weight Loss and Fever

If a knee joint pain or inflammation is associated with marked weight loss without any reason, general fatigue without doing much activity and high fever (with or without chills), it can be associated with some infectious disorder. This condition should not be ignored and needs immediate medical attention. Other alarming symptoms of knee disorder associated with infection are generalized weakness, inability to move the knee, severe pain, swelling, redness and warmth in the joint.